Acute Lung Injury Mortality Is 4-Fold Higher Than That From Heart Attack and Comparable to Breast Cancer and HIV, According to an Article Published...
Acute Lung Injury Mortality Is 4-Fold Higher Than That From Heart Attack and Comparable to Breast Cancer and HIV, According to an Article Published in Today's New England Journal of Medicine Thursday October 20, 9:55 am ET
SEATTLE, Oct. 20 /PRNewswire/ -- Acute Lung Injury (ALI) is responsible for 74,500 deaths each year in the United States.
Acute Lung Injury (ALI) strikes more than 190,000 Americans each year, causing approximately 74,500 deaths and 3.6 million hospital days, according to a study published in the New England Journal of Medicine.
"Acute lung injury is a critical illness syndrome consisting of acute hypoxemic respiratory failure with bilateral pulmonary infiltrates that are not attributable to left arterial hypertension," said Gordon Rubenfeld, M.D., professor, Harborview Medical Center. "Despite recent advances in our understanding of the mechanism and treatment of acute lung injury, its incidence in the United States has been unclear."
In the study, Incidence and Outcomes of Acute Lung Injury, a prospective, population based, cohort study was conducted in twenty-one hospitals in and around King County, Washington from April 1999 through July 2000, using a validated screening protocol to identify patients who met the consensus criteria for acute lung injury.
"The results," Dr. Rubenfeld explained, "indicate an in-hospital mortality rate for ALI of 38.5%. This is 4-fold higher than the mortality from a heart attack and attributable mortality comparable to breast cancer or HIV. The incidence and mortality increase with age."
"Only 1/3 of survivors are strong enough to be discharged directly home," said Dr. Rubenfeld. "Acute lung injury has a substantial impact on public heath, the incidence in the United States considerably higher than previous reports suggested."
"Sadly, most Americans have never heard of ALI or ARDS," said Eileen Rubin Zacharias, President of ARDS Foundation, a national not-for-profit organization dedicated to increasing public awareness, education, and financial assistance to those engaged in medical research of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). As a survivor of ARDS at the age of thirty-three, Ms. Zacharias knows first hand the cost of this critical illness. "After spending eight of my nine week hospitalization on a ventilator, I was unable to return to work for eight months."
Paula Blonski, Vice-President of ARDS Foundation, lost her sister, Marybeth, a nurse, at the age of thirty-six. "ALI and ARDS seriously lack public awareness, and as a result, ARDS research is severely under funded," said Ms. Blonski. "Should this study act as a catalyst to encourage continued medical research, the impact will be immeasurable."
To learn more about ARDS and the ARDS Foundation, please visit http://www.ardsusa.org or call 1.312.749.7047.
If you would like to speak to ARDS Foundation President, Eileen Rubin Zacharias, call 312.749.7047 or email info@ardsusa.org .
Other study authors include M.Sc., Ellen Caldwell, M.S., Eve Peabody, B.A., Jim Weaver, R.R.T., Diane P. Martin, Ph.D., Margaret Neff, M.D., Eric J. Stern, M.D., and Leonard D. Hudson, M.D.

